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Merck
  • Synthesis, characterization, and pharmacological evaluation of novel azolo- and azinothiazinones containing 2,4-dihydroxyphenyl substituent as anticancer agents.

Synthesis, characterization, and pharmacological evaluation of novel azolo- and azinothiazinones containing 2,4-dihydroxyphenyl substituent as anticancer agents.

Monatshefte fur chemie (2015-07-21)
Joanna Matysiak, Małgorzata Juszczak, Monika M Karpińska, Ewa Langner, Katarzyna Walczak, Marta Lemieszek, Alicja Skrzypek, Wojciech Rzeski, Andrzej Niewiadomy
要旨

We reported the synthesis and characterization of a series of azolo- and azino[1,3]thiazinones containing the 2,4-dihydroxyphenyl substituent. The compounds were prepared by a new one-step reaction of aryl-modified sulfinylbis[(2,4-dihydroxyphenyl)methanethione]s and the corresponding aminoazolo(azino)carboxamides. Their chemical structures were confirmed by IR, NMR:

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製品番号
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製品内容

Sigma-Aldrich
ジメチルスルホキシド-d6, 99.9 atom % D
Sigma-Aldrich
ジメチルスルホキシド-d6, 99.9 atom % D, contains 0.03 % (v/v) TMS
Sigma-Aldrich
ジメチルスルホキシド-d6, 99.5 atom % D
Sigma-Aldrich
メタノール, anhydrous, 99.8%
Sigma-Aldrich
ピリジン, anhydrous, 99.8%
Sigma-Aldrich
ジメチルスルホキシド-d6, "100%", 99.96 atom % D
Sigma-Aldrich
メタノール, JIS special grade, ≥99.8%
Sigma-Aldrich
ジメチルスルホキシド-d6, anhydrous, 99.9 atom % D
Sigma-Aldrich
ジメチルスルホキシド-d6, 99.9 atom % D, contains 1 % (v/v) TMS
Sigma-Aldrich
メタノール, SAJ first grade, ≥99.5%
Sigma-Aldrich
ピリジン, ≥99%
Sigma-Aldrich
ジメチルスルホキシド-d6, "100%", 99.96 atom % D, contains 0.03 % (v/v) TMS
Sigma-Aldrich
ジメチルスルホキシド-d6, "Special HOH", ≥99.9 atom % D
Sigma-Aldrich
メタノール, suitable for HPLC
Sigma-Aldrich
メタノール, SAJ special grade
Sigma-Aldrich
ピリジン, JIS special grade, ≥99.5%
Sigma-Aldrich
5-アミノ-4-イミダゾールカルボキサミド, 95%
Sigma-Aldrich
メタノール, NMR reference standard
Sigma-Aldrich
メタノール, HPLC Plus, ≥99.9%, poly-coated bottles
Sigma-Aldrich
メタノール, JIS 300, ≥99.8%, for residue analysis
Sigma-Aldrich
4-Amino-1-methyl-3-n-propyl-5-pyrazolecarboxamide, 96%
Supelco
メタノール 溶液, contains 0.10 % (v/v) formic acid, UHPLC, suitable for mass spectrometry (MS), ≥99.5%
Sigma-Aldrich
Methanol-12C, 99.95 atom % 12C
Sigma-Aldrich
ピリジン, suitable for hydroxyl value determination, ≥99.5%