1358503

ロイプロリド 酢酸塩

United States Pharmacopeia (USP) Reference Standard

• 別名: des-Gly¹⁰-[D-Leu⁶]-LH-RHエチルアミド, ロイプロレリン
• 実験式（ヒル表記法）: C₅₉H₈₄N₁₆O₁₂ · xC₂H₄O₂
• CAS番号: 74381-53-6
• 分子量: 1209.40 (free base basis)
• MDL番号: MFCD00167544
• UNSPSCコード: 41116107
• PubChem Substance ID: 329750244
• NACRES: NA.24

特性

• グレード: pharmaceutical primary standard
• APIファミリー: leuprolide
• メーカー／製品名: USP
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: −20°C
• SMILES記法: CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc5c[nH]cn5)NC(=O)[C@@H]6CCC(=O)N6
• InChI: 1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42-,43+,44-,45-,46-,47-,48-/m0/s1
• InChI Key: GFIJNRVAKGFPGQ-LIJARHBVSA-N
• 遺伝子情報: human ... GNRHR(2798)

詳細

Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Leu-Leu-Arg-Pro-NHEt

詳細

Leuprolide Acetate is a synthetic nonapeptide agonist analog of the luteinizing hormone-releasing factor. It contains not less than 97.0% and not more than 103.0 % of leuprolide, calculated on an anhydrous, acetic acid-free basis. Leuprolide Acetate USP Reference Standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

アプリケーション

Leuprolide Acetate USP reference standard is used to prepare standard solutions for the identification, assay, and determination of the purity of leuprolide acetate. Further information is available in monograph, Leuprolide Acetate, USP43-NF38 – 2572 of United States Pharmacopeia (USP).

アナリシスノート

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

その他情報

This product is part of the USP Biologics program.

Sales restrictions may apply.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable