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Merck
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資料

53848-U

Supelco

Ascentis® Express 90Å C8 (2.7 μm) HPLC Columns

L × I.D. 5 cm × 3 mm, HPLC Column

別名:

Core-shell (SPP) Fused Core C8 HPLC column

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About This Item

UNSPSCコード:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

アセンティス®エクスプレス C8, 2.7 μm HPLCカラム, 2.7 μm particle size, L × I.D. 5 cm × 3 mm

物質

stainless steel column

認証

suitable for USP L7

製品種目

Ascentis®

特徴

endcapped

メーカー／製品名

Ascentis®

包装

1 ea of

パラメーター

60 °C temp. range
600 bar max. pressure (9000 psi)

テクニック

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

L × 内径

5 cm × 3 mm

表面積

135 m2/g

不純物

<5 ppm metals

マトリックス

Fused-Core particle platform
superficially porous particle

マトリックス活性基

C8 (octyl) phase

粒径

2.7 μm

ポアサイズ

90 Å

operating pH range

2-9

アプリケーション

food and beverages

分離法

reversed phase

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詳細

アセンティス・エクスプレスHPLC カラムは、Fused-Core（フーズドコア）®粒子技術を用いることで、低い背圧を維持しながらサブ2 µm粒子の高速と高効率の両方を提供することができます。高い効率と低い背圧の組み合わせによって、従来のHPLC のユーザーだけではなくUPLC ®（または他の超高圧システム）のユーザーにも利益がもたらされます。
この新しいカラム技術のより詳細な情報については アセンティス・エクスプレスのホームページをご覧ください。

アプリケーション


  • Recent trends in ultra-fast HPLC: new generation superficially porous silica columns: This review explores advancements in high-performance liquid chromatography (HPLC), specifically focusing on the Ascentis® Express C8 column. Highlighting its role in achieving high-efficiency separations due to its design, this column is ideal for rapid, high-resolution chromatographic analysis in pharmaceutical, environmental, and material science applications (Ali et al., 2012).

  • Quality by design approach for the separation of naproxcinod and its related substances by fused core particle technology column: This research employs the Ascentis® Express C8 column, utilizing its high-efficiency and rapid separation capabilities to analyze naproxcinod and its impurities. The study exemplifies the column′s use in pharmaceutical quality control, ensuring drug purity and safety (Inugala et al., 2013).

法的情報

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
UPLC is a registered trademark of Waters

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保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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試験成績書（COA）

Lot/Batch Number
USPL001507
USPL001506
USPL001505
USPL001504
USPL001501

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文書ライブラリにアクセスする

Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Luigi Silvestro et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(30), 3134-3142 (2010-10-20)
Quantitative methods using LC-MS/MS allow achievement of adequate sensitivity for pharmacokinetic studies with clopidogrel; three such methods, with LLOQs as low as 5 pg/mL, were developed and fully validated according to the well established FDA 2001 guidelines. The chromatographic separations
Han Young Eom et al.
Journal of chromatography. A, 1217(26), 4347-4354 (2010-05-11)
Saikosaponins are triterpene saponins derived from the roots of Bupleurum falcatum L. (Umbelliferae), which has been traditionally used to treat fever, inflammation, liver diseases, and nephritis. It is difficult to analyze saikosaponins using HPLC-UV due to the lack of chromophores.
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when
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資料

Ascentis® Express C8 U/HPLC Columns

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

Chromatograms

application for HPLC

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