T8806

Thymopentin

≥97% (HPLC)

• 別名: TP5, Arg-Lys-Asp-Val-Tyr
• 実験式（ヒル表記法）: C₃₀H₄₉N₉O₉
• CAS番号: 69558-55-0
• 分子量: 679.76
• MDL番号: MFCD00214200
• UNSPSCコード: 12352209
• PubChem Substance ID: 329826886
• NACRES: NA.26

特性

• product name: Thymopentin, ≥97% (HPLC)
• 品質水準: 200
• アッセイ: ≥97% (HPLC)
• 形状: powder
• 色: white
• アプリケーション: cell analysis
• 保管温度: −20°C
• SMILES記法: CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
• InChI: 1S/C30H49N9O9/c1-16(2)24(28(46)38-22(29(47)48)14-17-8-10-18(40)11-9-17)39-27(45)21(15-23(41)42)37-26(44)20(7-3-4-12-31)36-25(43)19(32)6-5-13-35-30(33)34/h8-11,16,19-22,24,40H,3-7,12-15,31-32H2,1-2H3,(H,36,43)(H,37,44)(H,38,46)(H,39,45)(H,41,42)(H,47,48)(H4,33,34,35)/t19-,20-,21-,22-,24-/m0/s1
• InChI Key: PSWFFKRAVBDQEG-YGQNSOCVSA-N

詳細

Amino Acid Sequence

Arg-Lys-Asp-Val-Tyr

詳細

Thymopentin (TP5) is a pentapeptide produced by the epithelial cells of the thymic cortex and medulla. It consists of thymosin α1 (Tα1).

生物化学的／生理学的作用

Thymopentin (TP5) is an immunomodulator, resembling the active site of the thymopoietin. TP5 stimulates cellular immune responses such as T-cell formation, natural killer (NK) cell and macrophage activation, generation of cytokines, and activation of B-cell for antibody production. It also mimics the polypeptide environment of the thymus. TP5 is used to treat conditions like immune deficiency, autoimmune diseases, infections, and cancers. It has a short half-life and is rapidly metabolized in the gastrointestinal tract.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)