T4077

抗TAZ抗体 ウサギ宿主抗体

affinity isolated antibody, buffered aqueous solution

• 別名: Taz Antibody, Taz Antibody - Anti-TAZ antibody produced in rabbit, Anti-Transcriptional co-activator with PDZ-binding motif
• MDL番号: MFCD03792065
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen ~49 kDa
• 交差性: rat, human, mouse
• テクニック: immunohistochemistry: suitable; western blot: 1:500-1:1,000
• UniProtアクセッション番号: Q9GZV5
• 輸送温度: dry ice
• 保管温度: −20°C
• 遺伝子情報: human ... WWTR1(25937)

詳細

詳細

Tafazzin (TAZ) is encoded by the WW domain containing transcription regulator 1 (WWTR1) gene mapped to human chromosome Xq28. The encoded protein contains 400 amino acids. It is characterized by a conserved WW domain, implicated in binding PPXY motif, a coiled-coil region associated with protein-protein interaction and a C-terminal motif involved in binding the PDZ domain.

免疫原

synthetic peptide corresponding to residues 386-400 of human TAZ.

生物化学的／生理学的作用

Tafazzin (TAZ) plays a vital role in the various cellular process including cell proliferation, differentiation, apoptosis, migration, invasion, epithelial-mesenchymal transition (EMT) and stemness in multiple human cancers. TAZ associates with other transcription factors such as RUNX2 (runt-related transcription factor 2), PPAR (peroxisome proliferator-activated receptor), PAX3 and 8 (paired box gene 3 and 8) and TTF1 (thyroid transcription factor 1) and plays an essential role in osteoblastic, myogenic and adipogenic differentiation.

物理的形状

solution in phosphate buffered saline, containing 0.02% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)