SRP5266

HDAC2, active, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 別名: RPD3
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• リコンビナント: expressed in baculovirus infected Sf9 cells
• アッセイ: ≥70% (SDS-PAGE)
• フォーム: buffered aqueous glycerol solution
• 比活性: 3553-5520 RLU/min·ng
• 分子量: ~92 kDa
• NCBIアクセッション番号: NM_001527
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... HDAC2(3066)

詳細

詳細

HDAC2 or Histone deacetylase 2 belongs to the histone deacetylase family that acts via the formation of large multiprotein complexes, and is responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). HDAC2 forms transcriptional repressor complexes by associating with many different proteins and plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC2 functions in modulating synaptic plasticity and long-lasting changes of neural circuits, which in turn negatively regulates learning and memory. HDAC1 and HDAC2 are functionally redundant in cardiac growth and development and they maintain cardiomyocyte identity and function.

物理的形状

50 mM Tris-HCl溶液（pH 7.5、150 mM NaCl、10 mM グルタチオン、0.1 mM EDTA、0.25 mM DTT、0.1 mM PMSF、25％ グリセロール）

調製ノート

開封後は少量ずつに分注して－70℃で保管してください。操作を反復したり凍結融解を何度も繰り返したりしないでください。

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable