SRP0726

STK21 (CIT), Active

recombinant

• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• リコンビナント: expressed in baculovirus infected Sf9 cells
• アッセイ: 70-95% (SDS-PAGE)
• 形状: frozen liquid
• 比活性: 4.0-6.0 nmol/min·mg (radiometric)
• 分子量: ~74 kDa
• 濃度: 0.1 μg/μL
• アクセッション番号: NM_007174
• 輸送温度: dry ice
• 保管温度: −70°C
• 遺伝子情報: human ... STK21(11113)

詳細

アプリケーション

Useful for kinase assay and Western blot.

生物化学的／生理学的作用

Recombinant human STK21 (CIT) (1-449) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. STK21 is a serine/threonine-protein kinase that functions in cell division and also to promote efficient cytokinesis. STK21 is a novel molecular mechanism for a subset of human malformation syndromes of the central nervous system ⁽¹⁾. STK21 is also associated with bipolar disorder and risk for schizophrenia. STK21 is a novel partner for the GTP-bound forms of rho and rac ⁽²⁾.

再構成

Formulated in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

保管および安定性

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable