SML0551
Icaritin
≥98% (HPLC)
別名:
3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
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| サイズ/SKU | 在庫状況 | 単価 |
|---|---|---|
5 mg | カートの在庫状況を確認する | ￥17,600 |
25 mg | カートの在庫状況を確認する | ￥67,600 |
この商品について
実験式（ヒル表記法）:
C21H20O6
CAS番号:
分子量:
368.38
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
light yellow to dark yellow
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
COc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)c(C\C=C(\C)C)c3O2
InChI
1S/C21H20O6/c1-11(2)4-9-14-15(22)10-16(23)17-18(24)19(25)20(27-21(14)17)12-5-7-13(26-3)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3
InChI key
TUUXBSASAQJECY-UHFFFAOYSA-N
Biochem/physiol Actions
Icaritin enhances osteoblastic differentiation of mesenchymal stem cells (MSCs) while it inhibits adipogenic differentiation of MSCs.
Icaritin enhances osteoblastic differentiation of mesenchymal stem cells (MSCs). It may have estrogen-like activities.
Icaritin is a component of Epimedium flavonoid isolated from Herba Epimedii, which enhances osteoblastic differentiation of mesenchymal stem cells (MSCs) while it inhibits adipogenic differentiation of MSCs by inhibiting PPAR-g pathway. Icaritin has no effect on MSCs proliferation. Also, icaritin potently inhibits chronic myeloid leukemia (CML) and breast cancer cells proliferation most likely by modulation of MAPK/ERK/JNK and JAK2/STAT3 /AKT signaling. As other flavonoids, icaritin may exert estrogen-like activities.
Features and Benefits
This compound is featured on the JAKs, MAPKs and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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当該品目 | |||
|---|---|---|---|
| description ≥98% (HPLC) | description phyproof® Reference Substance | description ≥95% (HPLC), crystalline | description - |
| form powder | form - | form crystalline | form solid |
| assay ≥98% (HPLC) | assay ≥95.0% (HPLC) | assay ≥95% (HPLC) | assay 99% |
| Quality Level 100 | Quality Level - | Quality Level 200 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. - |
| solubility DMSO: 5 mg/mL, clear (warmed) | solubility - | solubility H2O: 0.3 mg/mL, ethanol: 35 mg/mL | solubility - |
| color light yellow to dark yellow | color - | color white | color - |
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保管分類
11 - Combustible Solids
WGK
WGK 3
引火点 (F)
Not applicable
引火点（°C）
Not applicable