SML0342

TFM-4AS-1

≥98% (HPLC)

• 別名: (4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-N-[2-(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11atetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
• 実験式（ヒル表記法）: C₂₇H₃₃F₃N₂O₂
• CAS番号: 188589-61-9
• 分子量: 474.56
• UNSPSCコード: 51111800
• PubChem Substance ID: 329825347
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: DMSO: >5 mg/mL
• 保管温度: 2-8°C
• SMILES記法: CN1[C@@H]2CC[C@@H]3[C@@H]4CC[C@H](C(=O)Nc5ccccc5C(F)(F)F)[C@@]4(C)CC[C@@H]3[C@@]2(C)C=CC1=O
• InChI: 1S/C27H33F3N2O2/c1-25-14-12-18-16(8-11-22-26(18,2)15-13-23(33)32(22)3)17(25)9-10-20(25)24(34)31-21-7-5-4-6-19(21)27(28,29)30/h4-7,13,15-18,20,22H,8-12,14H2,1-3H3,(H,31,34)/t16-,17+,18+,20-,22-,25+,26-/m1/s1
• InChI Key: YFBLEKKYWFJKBP-HNXMFXTHSA-N

詳細

生物化学的／生理学的作用

TFM-4AS-1 is a potent SARM (Selective Androgen Receptor Modulator). TFM-4AS-1 is a partial agonist of AR. The compound promotes the buildup of bone and muscle mass while having reduced effects on reproductive organs and sebaceous glands. The compound also is an inhibitor of rat 5 α-reductase enzymes type I (2 nM) and type 2 (3 nM).

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable