SAB4501174

Anti-Connexin 43 Antibody

rabbit polyclonal

• 別名: CX43, CXA1, CXN-43, Connexin 43, Gap junction 43 kDa heart protein
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 製品名: Anti-Connexin 43 antibody produced in rabbit, affinity isolated antibody
• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 43 kDa
• 交差性: mouse, human, rat
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:20000; western blot: 1:500-1:1000
• NCBIアクセッション番号: P17302
• UniProtアクセッション番号: P17302
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... GJA1(2697)

詳細

詳細

Connexin 43 belongs to the connexin protein family that forms gap junction. This protein is highly expressed in neurons and radial glia during development and in astrocytes in adult brains.

免疫原

The antiserum was produced against synthesized peptide derived from human Connexin 43.

Immunogen Range: 332-381

アプリケーション

Anti-Connexin 43, C-Terminal antibody produced in rabbit has been used in flow cytometry.[1]

生物化学的／生理学的作用

In rodents, connexin-43 (Cx-43) shows specific temporal patterns of expression during brain development. Experimental studies reveal that, connexin-43 expression increases in the brain during sheep ontogenesis.This protein might play a crucial role in neuronal migration as it resides in radial glial fibers which are closely associated with migrating neurons. It is also involved in transmembrane NAD⁺ transport. connexin-43, which is an element of gap junction, helps in cell–cell communication. Cx-43 is known to induce [Ca^2+] i burst phenomenon in uterine artery endothelial cells (UAECs).

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable