SAB4500930

Anti-MAST3 antibody produced in rabbit

affinity isolated antibody

• 別名: KIAA0561, MAST3, Microtubule-associated serine/threonine-protein kinase 3
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 143 kDa
• 交差性: mouse, human
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:10000; western blot: 1:500-1:1000
• NCBIアクセッション番号: O60307
• UniProtアクセッション番号: O60307
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MAST3(23031)

詳細

詳細

Anti-MAST3 Antibody detects endogenous levels of total MAST3 protein. Microtubule associated serine/threonine kinase 3 (MAST3) belongs to the MAST kinase family. It is composed of 1309 amino acids. The MAST3 gene is 53.9kb long and has 27 exons. It is localized on human chromosome 19p13.11. MAST3 possesses four α-helix bundles having various domains, including a protein kinase domain and a PDZ domain.

免疫原

The antiserum was produced against synthesized peptide derived from human MAST3.

Immunogen Range: 1031-1080

生物化学的／生理学的作用

Microtubule associated serine/threonine kinase 3 (MAST3) modulates the activity of nuclear factor κ-B (NF-κB). It may have a role in inflammatory pathways. Knockdown of MAST3 has been shown to reduce NF-κB activity, which is dependent on toll-like receptor-4.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable