Cluster of differentiation (CD63) belongs to the tetraspanin family, with four transmembrane domains. It is localised in late endosomes and lysosomes. The gene is located on human chromosome 12q13.2. CD63 is a membrane bound glycoprotein.
免疫原
Synthetic peptide of human CD63 molecule
生物化学的/生理学的作用
Cluster of differentiation (CD63) acts as a platelet activation marker. It plays an important role in regulating cell proliferation, adhesion, motility and differentiation. CD63 acts as a prognostic marker for lung adenocarcinoma. Deficiency of CD63 is associated with Hermansky−Pudlak syndrome (HPS).
特徴および利点
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物理的形状
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
The American journal of pathology, 191(12), 2147-2171 (2021-08-25)
Three-dimensional (3D) imaging and quantitative analysis of extracellular vesicles (EVs) remain largely unexplored, mainly because of limitations in detection techniques. In this study, EVs from patients diagnosed with colorectal cancer (CRC) and ulcerative colitis were examined. To investigate the spatial
Course of platelet activation markers after ischemic stroke
Marquardt L, et al.
Stroke, 33(11), 2570-2574 (2002)
Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function
Wei ML
Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 19(1), 19-42 (2006)