SAB4300094

Anti-phospho-FOXO1 (pSer²⁵⁶) antibody produced in rabbit

affinity isolated antibody

• 別名: 抗FKH1抗体 ウサギ宿主抗体, 抗FKHR抗体 ウサギ宿主抗体, 抗FOXO1A抗体 ウサギ宿主抗体
• MDL番号: MFCD03791549
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: IF; IHC (p); WB
• クローン: polyclonal
• 化学種の反応性: rat, human, mouse
• citations: 10
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: 78-82 kDa
• 化学種の反応性: rat, human, mouse
• 濃度: 1 mg/mL
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• アイソタイプ: IgG
• 免疫原配列: (A-A-SP-M-D)
• NCBIアクセッション番号: NP_002006.2
• UniProtアクセッション番号: Q12778
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer256)
• 遺伝子情報: human ... FOXO1(2308)

詳細

詳細

FOXO1 (forkhead box O1) is encoded by the gene mapped to human chromosome 13q14. The encoded protein is a transcription factor and is a member of the Foxo subfamily.

免疫原

Peptide sequence around phosphorylation site of serine 256 (A-A-S(p)-M-D), according to the protein FOXO1.

アプリケーション

Anti-phospho-FOXO1 (pSer256) antibody produced in rabbit has been used in western blotting.

生物化学的／生理学的作用

FOXO1 (forkhead box O1) blocks the differentiation of cell in fetal pancreatic progenitor cells. It controls the differentiation of adipocytes. FOXO1 is involved in the insulin regulation of glucose-6-phosphatase (G6p) expression. Additionally, this protein plays a vital role in tumor suppression by inducing growth arrest and apoptosis.

特徴および利点

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ターゲットの説明

Transcription factor.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable