SAB4200650

Monoclonal Anti-SH3GL1 (C-terminal) antibody produced in mouse

clone Ep2.17, purified from hybridoma cell culture

• 別名: Anti-CNSA1, Anti-EEN, Anti-SH3D2B, Anti-SH3P8
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: Ep2.17, monoclonal
• フォーム: buffered aqueous solution
• 分子量: ~41 kDa
• 交差性: human
• 濃度: ~1 mg/mL
• テクニック: flow cytometry: 2-5 μg/test using using HeLa cells.; immunoblotting: 1-2 μg/mL using whole extracts of HeLa.
• アイソタイプ: IgG2b
• UniProtアクセッション番号: Q99961
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SH3GL1(6455)

詳細

詳細

Monoclonal Anti-SH3GL1 (C-terminal) (mouse IgG2b isotype) is derived from the hybridoma Ep2.17 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. SH3GL1 (SH3-domain GRB2-like 1), also known as endophilin-A2, is a member of the endophilin family of Src homology 3 (SH3) domain-containing proteins. The SH3 domain drives protein-protein interactions through binding to proline-rich ligands. The SH3GL proteins have a novel N-terminal segment, and a peculiar tissue distribution: SH3GL1 is ubiquitous, SH3GL2 located in the brain, and SH3GL3 in brain and testis.

免疫原

a synthetic peptide corresponding to a sequence at the C-terminal region of human SH3GL1

アプリケーション

Monoclonal Anti-SH3GL1 (C-terminal) antibody produced in mouse has been used in immunoblotting and flow cytometry.

生物化学的／生理学的作用

SH3GL1 is involved in several brain tumors, such as glioma, where its levels were increased in proportion to the tumor progression. In cells generated from children malignant brain tumor medulloblastoma (MB), SH3GL1 expression was found to be regulated by the miRNA, miR-218.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable