SAB4200508

Anti-ARG1 antibody, Mouse monoclonal

clone ARG1-3, purified from hybridoma cell culture

• 別名: Anti-arginase-1, Anti-liver-type arginase, Anti-type I arginase, Monoclonal Anti-ARG1 antibody produced in mouse
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: ARG1-3, monoclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~40 kDa
• 化学種の反応性: rat, human, mouse
• 濃度: ~1.0 mg/mL
• テクニック: western blot: 2-4 μg/mL using whole extracts of rat or mouse liver.
• UniProtアクセッション番号: P05089
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ARG1(383)

詳細

詳細

Monoclonal Anti-ARG1 (mouse IgG1 isotype) is derived from the hybridoma ARG1-3 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide. Arginase (ARG)1 gene, codes for type I isoform of arginase. ARG1 is a cytosolic enzyme expressed predominantly in the liver as a component of the urea cycle.

免疫原

synthetic peptide corresponding to a sequence at the N-terminal region of human ARG1, conjugated to KLH. The corresponding sequence differs by 3 amino acids in mouse ARG1 and by 4 amino acids in rat ARG1.

アプリケーション

Monoclonal Anti-ARG1 antibody produced in mouse has been used in immunoblotting.

生物化学的／生理学的作用

Arginase hydrolyzes arginine to ornithine and urea. Arginases have been implicated in many disease processes, including vascular diseases, pulmonary diseases, infectious diseases, immune cell dysfunction and cancer. Inherited deficiency of ARG1 enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable