Anti-VIP36/LMAN2 is produced in rabbit using as immunogen a synthetic peptide of human LMAN2 conjugated to KLH. VIP36 (vesicular-integral protein of 36 kDa) is a member of the leguminous-type (L-type) lectin family, which also includes ERGIC-53, ERGL and VIPL. L-type lectins are type I transmembrane proteins composed of a large luminal domain comprising a carbohydrate recognition domain (CRD) and a short cytosolic domain that mediates sorting within the early secretory pathway. VIP36 localizes mainly to the Golgi apparatus and cycles between the Golgi and the ER.
アプリケーション
Anti-VIP36/ LMAN2 antibody produced in rabbit has been used in immunoblotting.
生物化学的／生理学的作用
Vesicular-integral protein of 36 kDa (VIP36) binds high mannose type glycoproteins in a Ca2+-dependent manner and may facilitate their sorting, trafficking and quality control.
物理的形状
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
免責事項
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