SAB4200182

Anti-Glutathione Reductase antibody, Mouse monoclonal

clone GR6, purified from hybridoma cell culture

• 別名: 抗GR抗体, 抗GSR抗体
• MDL番号: MFCD01323367
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: GR6, monoclonal
• フォーム: buffered aqueous solution
• 分子量: antigen ~55 kDa
• 交差性: human
• 濃度: ~1.0 mg/mL
• テクニック: immunoprecipitation (IP): suitable; western blot: 2-4 μg/mL using whole extracts of human HepG2 cells.
• アイソタイプ: IgG1
• UniProtアクセッション番号: P00390
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... GSR(2936)

詳細

詳細

Monoclonal Anti-Glutathione Reductase (mouse IgG1 isotype) is derived from the hybridoma GR6 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a human Glutathione reductase recombinant protein. Glutathione reductase is a homodimeric enzyme containing one FAD molecule and NADPH binding domain per subunit. This gene is located on human chromosome 8p.

免疫原

mice immunized with a human Glutathione reductase recombinant protein. The corresponding proteins in rat and mouse share 86% and 85% homology, respectively.

アプリケーション

Monoclonal Anti-Glutathione Reductase antibody produced in mouse has been used in:

• immunohistochemical
• immunofluorescence studies
• immunoblotting
• immunoprecipitation

生物化学的／生理学的作用

Glutathione reductase (GR) is a ubiquitous flavoenzyme involved in protecting cells from stress. GR catalyses the reduction of oxidized glutathione (GSSG) to glutathione (GSH). It is an essential component of the glutathione redox cycle, which maintains adequate levels of reduced cellular GSH. GSH serves as an antioxidant and also as an electron donor for glutathione peroxidases and a substrate for glutathione-S-transferases.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable