SAB3501212

Anti-West Nile Virus Envelope antibody produced in rabbit

affinity isolated antibody

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: liquid
• 化学種の反応性: West Nile virus
• 濃度: 1 mg/mL
• テクニック: ELISA: suitable
• アイソタイプ: IgG
• NCBIアクセッション番号: NP_776014
• UniProtアクセッション番号: P06935
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.

免疫原

West Nile virus envelope antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of the West Nile Virus envelope protein.The immunogen is located within amino acids 740 - 790 of West Nile Virus Envelope.

アプリケーション

West Nile virus envelope protein antibody can be used for the detection of the West Nile virus envelope protein in ELISA. It will detect 10 ng of free peptide at 1 μg/mL.

物理的形状

Supplied in PBS containing 0.02% sodium azide.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable