SAB3500068

Anti-EPHA10 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-EPH receptor A10, Anti-Ephrin type-A receptor 10, Anti-FLJ16103
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: mouse, rat, human
• テクニック: indirect ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: NP_001092909
• UniProtアクセッション番号: Q5JZY3
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... EPHA10(284656)

詳細

免疫原

EphA10 antibody was raised against a 14 amino acid peptide of near the amino terminus of human EphA10.

特徴および利点

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ターゲットの説明

Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell–cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.

関連事項

The action of this antibody can be blocked using blocking peptide SBP3500068.

物理的形状

約1 mg/mLのPBS (0.02％ アジ化ナトリウム含有)

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable