SAB3500013

Anti-MTCH2 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-Mitochondrial carrier homolog 2
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: mouse, human
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: AAD52647
• UniProtアクセッション番号: Q791V5
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Mtch2(56428)

詳細

免疫原

MTCH2 antibody was raised against a 15 amino acid peptide near the amino terminus of human MTCH2.

特徴および利点

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ターゲットの説明

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.

関連事項

The action of this antibody can be blocked using blocking peptide SBP3500013.

物理的形状

約1 mg/mLのPBS (0.02％ アジ化ナトリウム含有)

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable