SAB2701455

Anti-DYNC1LI1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: DNCLI1, DYNC1LI1, FLJ10219
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: human, rat, mouse
• テクニック: immunohistochemistry: suitable; immunoprecipitation (IP): suitable; indirect immunofluorescence: suitable; western blot: 1000-10000
• NCBIアクセッション番号: AAI31621
• UniProtアクセッション番号: Q9Y6G9
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... DYNC1LI1(51143)

詳細

免疫原

Recombinant fragment corresponding to a region within amino acids 318 and 523 of DYNC1LI1 according to AAI31621

アプリケーション

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, IP: 1:100-1:500, WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生物化学的／生理学的作用

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

免責事項

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable