SAB2501514

Anti-KLHL6 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-FLJ00029, Anti-kelch-like 6, Kelch-like 6 (Drosophila), Kelch-like protein KLHL6
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: goat
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: rat, canine, human, mouse
• テクニック: indirect ELISA: suitable; western blot: suitable
• UniProtアクセッション番号: Q8WZ60
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... KLHL6(89857)

詳細

詳細

Kelch-like protein 6 (KLHL6) is a member of BTB (broad-complex, tramtrack and bric à brac)-kelch protein family. The gene encoding this protein is mapped to human chromosome 3q27. The encoded protein expression is confined to lymphoid tissue. KLHL6 exhibits high activity within the germinal center of B cells. The protein structure consists of a BTB domain at N terminal and six kelch repeats at the C terminal. KLHL6 protein is primarily expressed in human tonsil B lymphocytes.

Kelch-like protein 6 (KLHL6) plays a vital role in B-cell receptor (BCR) cell signaling and differentiation pathway of germinal center within B- cells. Aberration in the expression of this protein leads to chronic lymphocytic leukemia (CLL).

免疫原

Peptide with sequence SERTKPRMHEFQSE, from the internal region of the protein sequence according to NP_569713.2

特徴および利点

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物理的形状

20mM Tris（pH 7.3）、150mM NaCl、0.02％ アジ化ナトリウム、0.5％ ウシ血清アルブミン含有）を含む溶液中に0.5 mg/mLの濃度で提供されます。

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable