SAB2500422

抗FOXP3/スクルフィン抗体 ヤギ宿主抗体

affinity isolated antibody, buffered aqueous solution

• 別名: 抗AIID抗体, 抗IPEX抗体, 抗JM2抗体, 抗Scurfin抗体, 抗フォークヘッドボックスP3抗体
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: goat
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: human
• テクニック: flow cytometry: suitable; immunocytochemistry: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProtアクセッション番号: Q9BZS1
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... FOXP3(50943)

詳細

詳細

Forkhead box P3 (FOXP3) is a transcription factor and part of the forkhead family. It possesses three α helices and three β strands. The protein has an amino-terminal region, a central zinc finger, a leucine zipper domain and the carboxyl-terminal region has a forkhead domain. The gene encoding this protein is localized on human chromosome Xp11.23.

免疫原

NP_054728.2によるタンパク質配列のC末端に由来するペプチド(SQRPSRCSNPTPGP)。

生物化学的／生理学的作用

Forkhead box P3 (FOXP3) associates with nuclear factor of activated T cells (NFAT) and nuclear factor κ B (NF-κB). It has a crucial role in the cellular differentiation of regulatory T cells. Alterations in the protein expression have been associated with immunodysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome. FOXP3 has a role in tumor growth and cancer.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

0.5 mg/mL Tris緩衝生理食塩水(0.5% BSA, 0.02%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable