SAB2109030

Anti-IAPP (N-terminal) antibody produced in rabbit

affinity isolated antibody

• 別名: AMYLIN, DAP, IAP
• UNSPSCコード: 12352203
• NACRES: NA.43

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: 4 kDa
• 交差性（ホモロジーによる予測）: canine, rabbit, bovine, horse, human
• 濃度: 0.5 mg/mL
• テクニック: western blot: 1 μg/mL
• NCBIアクセッション番号: NM_000415
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... IAPP(57396)

詳細

詳細

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer′s disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

免疫原

Synthetic peptide directed towards the N terminal region of human IAPP

シーケンス

Synthetic peptide located within the following region: MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLV

物理的形状

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable