IST1 is proposed to be involved in specific functions of the ESCRT machinery. It is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvment in the MVB pathway is not established. IST1 is involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
免疫原
Synthetic peptide directed towards the N-terminal region of Human IST1
シーケンス
Synthetic peptide located within the following region: INRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEA
物理的形状
Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.