由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen ~48 kDa
化学種の反応性
human
テクニック
western blot: 1:500-1:1,000 using brain lysate
UniProtアクセッション番号
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... NPFFR1(64106)
詳細
Neuropeptide FF receptor 1 (NPFF1) is a receptor for the protein RFamide-related peptide-3 (RFRP-3). It is expressed in the ovaries and the gene encoding it is localized on human chromosome 10q21.
免疫原
peptide corresponding to the C-terminal sequence (amino acids 418-430) and N-terminal sequence (amino acids 1-16) of the NPFF1 protein.
生物化学的/生理学的作用
Neuropeptide FF receptor 1 (NPFF1) along with its ligand, prevents gonadotropin signaling.
物理的形状
Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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最新バージョンのいずれかを選択してください:
Identification and characterization of two G protein-coupled receptors for neuropeptide FF.
Bonini JA
The Journal of Biological Chemistry, 275(50), 39324-39331 (2000)
Hajime Oishi et al.
Endocrinology, 153(7), 3435-3445 (2012-06-14)
RFamide-related peptide-3 (RFRP-3), a mammalian ortholog of avian gonadotropin-inhibitory hormone, has pronounced inhibitory effects on reproduction in a number of species. RFRP-3 suppresses gonadotropin release at the hypothalamic and/or pituitary levels; however, increasing evidence also suggests putative functions within the
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