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Merck

K1769

Sigma-Aldrich

抗KTN1抗体 ウサギ宿主抗体

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

別名:

抗CG-1抗原抗体, 抗キネクチン1(キネシンレセプター)抗体

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

分子量

antigen ~150 kDa

交差性

human

包装

antibody small pack of 25 μL

濃度

~1.0 mg/mL

テクニック

immunoprecipitation (IP): 2-5 μg using lysate of Raji cells
indirect immunofluorescence: 2-5 μg/mL using human HeLa cells
western blot: 1-2 μg/mL using whole extract of human HeLa cells

UniProtアクセッション番号

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... KTN1(3895)

詳細

Kinectin (KTN1) protein is mainly located in the endoplasmic (ER) reticulum and is a large integral protein. This protein is made up of an N-terminal transmembrane domain and a C-terminal kinesin-binding domain. The KTN1 gene is mapped on the human chromosome at 14q22.3.

特異性

Anti-KTN1 recognizes human KTN1.

アプリケーション

Anti-KTN1 antibody produced in rabbit may be used in:
  • immunoblotting
  • immunoprecipitation
  • immunofluorescence

生物化学的/生理学的作用

Kinectin (KTN1) protein coheres to kinesin and is involved in vesicle transport on microtubules. This protein is also related to fibronectin-integrin adhesion sites.

物理的形状

0.01 M PBS溶液(pH 7.4, 15 mMアジ化ナトリウム含有)。

保管および安定性

Store at at –20 °C. For continuous use, the product may be stored at 2–8 °C for up to one month. For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Derrek P Hibar et al.
Nature, 520(7546), 224-229 (2015-01-22)
The highly complex structure of the human brain is strongly shaped by genetic influences. Subcortical brain regions form circuits with cortical areas to coordinate movement, learning, memory and motivation, and altered circuits can lead to abnormal behaviour and disease. To
Huan Tran et al.
Journal of cell science, 115(Pt 10), 2031-2040 (2002-04-26)
Integrin receptors mediate the formation of adhesion complexes and play important roles in signal transduction from the extracellular matrix. Integrin-based adhesion complexes (IAC) contain proteins that link integrins to the cytoskeleton and recruit signaling molecules, including vinculin, paxillin, focal adhesion
Lee-Lee Ong et al.
The Journal of biological chemistry, 281(44), 33621-33634 (2006-09-05)
Kinectin is an integral membrane protein with many isoforms primarily found on the endoplasmic reticulum. It has been found to bind kinesin, Rho GTPase, and translation elongation factor-1delta. None of the existing models for the quaternary organization of the elongation

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