GW21310

Anti-RGS7 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• 別名: 抗Gタンパク質シグナル伝達調節因子7 (Regulator of G-protein signaling7) 抗体
• UNSPSCコード: 12352203

特性

• 由来生物: chicken
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: rat, mouse, human
• メーカー／製品名: Genway 15-288-21310
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_002915.1
• UniProtアクセッション番号: P49802
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... RGS7(6000)

詳細

詳細

RGS7 (regulator of G-protein signaling 7) is a member of the R7 subfamily of RGS superfamily of regulators, and shares high homology with RGS9-2. It is composed of the catalytic RGS domain, a dishevelled, EGL-10 and pleckstrin (DEP) domain in its N-terminal, along with a G protein γ subunit-like (GGL) domain. It is both a soluble cytosolic protein as well as a membrane protein.

免疫原

Immunogen Sequence: GI # 11140809, sequence 227-262

Recombinant regulator of G-protein signalling 7

アプリケーション

Anti-RGS7 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生物化学的／生理学的作用

Regulator of G-protein signaling 7 belongs to a subfamily of regulator of G protein signaling (RGS) proteins, which modulate G protein signaling by acting as GTPase-activating proteins for G protein α-subunits. RGS7 exists as a dimer with the G protein β(5)-subunit. It plays a major role in the pathogenesis of panic disorder (PD). RGS7 has a potential role in neurons communicating between classical heterotrimeric G protein subunits and/or their effectors at the plasma membrane and the cell nucleus. It helps in regulating signaling by μ-opioid receptor (MOR) and dopamine D2 receptor (D2R) and are implicated in drug addiction, movement disorders and nociception.

物理的形状

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)