G5791

Anti-phospho-Glycogen Synthase Kinase 3α/β (pTyr^279/216) antibody produced in rabbit

affinity isolated antibody, aqueous glycerol solution

• 別名: Anti-phospho-GSK α/β (pTyr^279/216)
• MDL番号: MFCD03455745
• UNSPSCコード: 12352203
• NACRES: NA.44

特性

• 由来生物: rabbit
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: aqueous glycerol solution
• 分子量: antigen 47-51 kDa
• 化学種の反応性: human, mouse, rat
• テクニック: dot blot: suitable; indirect ELISA: suitable; western blot: 1:1000 using MCF-7 cell extract
• UniProtアクセッション番号: P49840
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr279/pTyr216)
• 遺伝子情報: human ... GSK3A(2931) ; mouse ... Gsk3a(606496) ; rat ... Gsk3a(50686)

詳細

詳細

GSK-3 functions a serine-threonine kinase and modulates a wide range of cellular activities such as cell signaling, cell cycle, cell growth and differentiation. Mammalian GSK-3 has two isoforms, namely, GSK-3α and GSK-3 β. GSK-3α has been implicated in Alzheimer′s disease, whereas both, GSK-3α and GSK-3β have been implicated in leukemia . Anti-phospho-Glycogen Synthase Kinase 3α/β (p(Tyr279/216)) antibody is specific for phosphorylated forms of GSK-3α (51 kDa) and GSK-3β (47 kDa) that contain a phosphate moiety on tyrosine 279 and 216 respectively. The antibody does not bind to non-tyrosine phosphorylated GSK-3α/β protein. The product recognizes human, mouse and rat GSK-3α/β.

免疫原

GSK-3α/βのチロシン^279/216を含む領域に由来する合成リン酸化ペプチド。

アプリケーション

Anti-phospho-Glycogen Synthase Kinase 3α/β (p(Tyr279/216)) antibody is suitable for use in indirect ELISA, dot blot and western blot (1:1000 using MCF-7 cell extract).

物理的形状

ダルベッコPBS溶液(Mg²⁺およびCa²⁺不含, pH 7.3, 50%グリセロ-ル, 1.0mg/mL BSA(IgGおよびプロテア-ゼフリ-), 0.05%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)