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10 MG
￥30,000
50 MG
￥114,000
About This Item
化学式:
C14H24N6O4C2H4O2
CAS番号:
分子量:
400.43
MDL番号:
UNSPSCコード:
51111800
PubChem Substance ID:
NACRES:
NA.32
品質水準
アッセイ
≥97% (TLC)
組成
Peptide content, ~70%
保管温度
−20°C
SMILES記法
CC(O)=O.NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN)C(O)=O
InChI
1S/C14H24N6O4.C2H4O2/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;1-2(3)4/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);1H3,(H,3,4)/t10-,11-;/m0./s1
InChI Key
MGNUTAFMLGJBGV-ACMTZBLWSA-N
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Amino Acid Sequence
Gly-His-Lys
詳細
Gly-His-Lys is a tripeptide present at ∼200ng/ml in association with α-globulin and albumin, in human blood plasma.[1]
アプリケーション
Gly-His-Lys (GHK) has been used for the preparation of post-operative intra-articular injection of GHK-Cu (copper).[2]
Gly-His-Lys acetate salt has been used:
- individually or as a complex with copper to test its effect on cytokines production in the human normal fibroblasts cell lines[3]
- as a model peptide in N,N-dimethyl-N-methacryloxyethyl-N-(3-sulfopropyl)ammonium betaine based capillary electrophoresis separation studies[4]
- as a component of Coon′s modified Ham′s F-12 medium for culturing Fischer rat thyroid follicular cell line, FRTL-5[5]
生物化学的／生理学的作用
包装
底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
G1887-VAR:
G1887-BULK:
G1887-50MG:
G1887-5MG:
G1887-10MG:
L Pickart et al.
Journal of chromatography, 175(1), 65-73 (1979-07-11)
Isolation and purification of growth-modulating peptides from biological sources is often accompanied by excessive losses of bioactive material. During the isolation of a growth-modulating tripeptide glycylhistidyllysine (GHL) from human plasma, copper and iron were found to co-isolate with the peptide.
Growth-modulating human plasma tripeptide: relationship between molecular structure and DNA synthesis in hepatoma cells.
L Pickart et al.
FEBS letters, 104(1), 119-122 (1979-08-01)
Jingyuan Xiong et al.
Drug and chemical toxicology, 41(4), 501-508 (2017-11-17)
Thyroid hormones are involved in many important physiological activities including regulation of energy metabolism, development of nervous system, maintenance of cerebral functions, and so on. Endocrine-disrupting chemicals (EDCs) that interfere with thyroid functions raise serious concerns due to their frequent
Wen Jiang et al.
Analytical chemistry, 75(11), 2768-2774 (2003-09-02)
A novel capillary with covalently bonded zwitterionic surface modification was prepared by photograft polymerization of the zwitterionic monomer N,N-dimethyl-N-methacryloxyethyl-N-(3-sulfopropyl)ammonium betaine, onto the inner surface of a UV-transparent fused-silica capillary. Although the zwitterionic moieties in the resulting polymeric "tentacles" comprise both
A Siméon et al.
The Journal of investigative dermatology, 115(6), 962-968 (2000-12-20)
Glycyl-histidyl-lysine-Cu(2+) is a tripeptide-copper complex previously shown to be an activator of wound healing. We have investigated the effects of glycyl-histidyl-lysine-Cu(2+) on the synthesis of glycosaminoglycans and small proteoglycans in a model of rat experimental wounds and in rat dermal
アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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