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由来生物
horse spleen
品質水準
無菌性
sterile-filtered
形状
liquid
濃度
10 mg/mL in 0.15 M NaCl
テクニック
cell culture | mammalian: suitable
electron microscopy: suitable
UniProtアクセッション番号
保管温度
2-8°C
遺伝子情報
horse ... FTL(100051593)
詳細
Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and ferritin are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.
アプリケーション
A cationic derivative used to label negatively charged cell membranes for visualization by electron microscopy.
Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.
Ferritin, cationized from horse spleen has been used:
- to incubate amoebae (106) in the study, to determine whether trophozoites are able to take up ferritin and internalise this protein for their growth in axenic culture
- to determine phagosome-lysosome fusion by electron microscopy
- to label freshly excised chick optic tecta in serum free incubation medium
生物化学的/生理学的作用
Ferritin holds iron at its ferric state (Fe3+). The core of ferritin has the capability to hold 4500 iron molecules. It is essential to store iron in vertebrates. Ferritin is also essential to store and transport iron in invertebrates. It plays a key role in dietary iron absorption.
調製ノート
ウマ脾臓フェリチンとN,N-ジメチル-1,3-プロパンジアミン (DMPA)とを共役させることにより調製。
保管分類コード
10 - Combustible liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
F7879-PH:
F7879-2ML-PW:
F7879-BULK:
F7879PROC:
F7879-2ML:
F7879-VAR:
試験成績書(COA)
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Scientific reports, 7, 44862-44862 (2017-03-24)
Once penetrated into the lungs of exposed people, asbestos induces an in vivo biomineralisation process that leads to the formation of a ferruginous coating embedding the fibres. The ensemble of the fibre and the coating is referred to as asbestos
Interaction of Legionella pneumophila with Acanthamoeba castellanii: uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion.
Infection and Immunity, 64(2), 668-673 (1996)
The Journal of physiology, 445, 473-486 (1992-01-01)
1. We have investigated the interaction of plasma proteins with the endothelial cell using cationized ferritin as a marker of the cell surface glycocalyx. 2. Single microvessels of the frog mesentery were sequentially perfused using glass micropipettes with solutions containing
American journal of physiology. Renal physiology, 321(3), F293-F304 (2021-07-21)
Kidney pathologies are often highly heterogeneous. To comprehensively understand kidney structure and pathology, it is critical to develop tools to map tissue microstructure in the context of the whole, intact organ. Magnetic resonance imaging (MRI) can provide a unique, three-dimensional
Iron-Induced Retinal Damage
Handbook of nutrition, diet, and the eye, 619-626 (2014)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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