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主要文書

原産地証明書（COO）/試験成績書（COA）

EHU077321

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human PTK2

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About This Item

UNSPSCコード:

41105324

NACRES:

NA.51

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Sigma-Aldrich

EMU068001

MISSION^® esiRNA

Sigma-Aldrich

407283

ペンタ-/ヘキサ-アクリル酸ジペンタエリスリトール

Supelco

08168

Timestrip Plus^™ 8°C

Sigma-Aldrich

246794

ペンタエリスリトールテトラアクリレート、ペンタエリスリトールトリアクリレート、およびトリメチロールプロパントリアクリレートの混合物

Sigma-Aldrich

SIC001

MISSION^® siRNA Universal Negative Control #1

Sigma-Aldrich

Z202843

Solvent still heads

Sigma-Aldrich

EHU110791

MISSION^® esiRNA

SML3760

TFMT

Sigma-Aldrich

EHURLUC

MISSION^® esiRNA

Sigma-Aldrich

D203203

ジペンタエリトリトール

詳細

品質水準

100

製品種目

MISSION^®

フォーム

lyophilized powder

esiRNA cDNA標的配列

CAATCCCACACATCTTGCTGACTTCACTCAAGTGCAAACCATTCAGTATTCAAACAGTGAAGACAAGGACAGAAAAGGAATGCTACAACTAAAAATAGCAGGTGCACCCGAGCCTCTGACAGTGACGGCACCATCCCTAACCATTGCGGAGAATATGGCTGACCTAATAGATGGGTACTGCCGGCTGGTGAATGGAACCTCGCAGTCATTTATCATCAGACCTCAGAAAGAAGGTGAACGGGCTTTGCCATCAATACCAAAGTTGGCCAACAGCGAAAAGCAAGGCATGCGGACACACGCCGTCTCTGTGTCAGAAACAGATGATTATGCTGAGATTATAGATGAAGAAGATACTTACACCATGCCCTCAACCAGGGATTATGAGATTCAAAGAGAAAGAATAGAACTTGGACGATGTATTGGAGAAGGCCAATTTGGAGATG

Ensembl |ヒトアクセッション番号

ENSG00000169398

NCBIアクセッション番号

NM_153831

輸送温度

ambient

保管温度

−20°C

遺伝子情報

human ... PTK2(5747) , PTK2(5747)

詳細

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法的情報

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

10 - Combustible liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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Capn4 contributes to tumor invasion and metastasis in clear cell renal cell carcinoma cells via modulating talin-focal adhesion kinase signaling pathway.

Qianfeng Zhuang et al.

Acta biochimica et biophysica Sinica, 50(5), 465-472 (2018-04-13)

Calpain small subunit 1 (Capn4) has been shown to correlate with the metastasis/invasion of clear cell renal cell carcinoma (ccRCC). This study aimed to further elucidate the molecular mechanisms underlying Capn4-mediated ccRCC progression. The mRNA expression levels in ccRCC cells

Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship.

Irina M Shapiro et al.

Science translational medicine, 6(237), 237ra68-237ra68 (2014-05-23)

The goal of targeted therapy is to match a selective drug with a genetic lesion that predicts for drug sensitivity. In a diverse panel of cancer cell lines, we found that the cells most sensitive to focal adhesion kinase (FAK)

Lidocaine inhibits the metastatic potential of ovarian cancer by blocking NaV 1.5-mediated EMT and FAK/Paxillin signaling pathway.

Chang Liu et al.

Cancer medicine, 10(1), 337-349 (2020-12-07)

Lidocaine, one of the most commonly used local anesthetics during surgery, has been reported to suppress cancer cell growth via blocking voltage-gated sodium channels (VGSCs). VGSC 1.5 (NaV 1.5) is highly expressed in invasive cancers including ovarian cancer. This study

Substrate Rigidity Controls Activation and Durotaxis in Pancreatic Stellate Cells.

Dariusz Lachowski et al.

Scientific reports, 7(1), 2506-2506 (2017-06-02)

Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive malignancy characterised by the presence of extensive desmoplasia, thought to be responsible for the poor response of patients to systemic therapies. Pancreatic stellate cells (PSCs) are key mediators in the production of this

High Expression of Integrin α3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer.

Qiqiao Du et al.

Frontiers in oncology, 10, 36-36 (2020-03-03)

Background: Cervical cancer remains a leading cause of death in women due to metastasis to distant tissues and organs. Integrins are involved in cancer metastasis. However, whether integrin α3 participates in cervical cancer metastasis is under investigation. In this study

主要文書

MISSION^® esiRNA