A3352
アシルコエンザイムA合成酵素 Pseudomonassp. （シュードモナス）由来
≥2 units/mg protein
別名:
酸:CoAリガーゼ(AMP生成)
ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
| あなたへ/カタログ番号 | 在庫状況 | 単価 |
|---|---|---|
1 unit | カートの在庫状況を確認する | ￥39,200 |
10 units | カートの在庫状況を確認する | ￥196,000 |
この商品について
CAS番号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-747-5
MDL number:
Specific activity:
≥2 units/mg protein
General description
Acyl-coenzyme A synthetase belongs to adenylate-forming enzymes superfamily. It has a conserved adenosine triphosphate/adenosine monophosphate (ATP/AMP) binding motif.
Application
Acyl-coenzyme A Synthetase may be used to study fatty acid metabolism and lipid metabolism. It has been used to study its interaction with fatty acid transport proteins, which has been found to be involved in the efficient cellular uptake of long-chain fatty acids in adipocytes [1].
Acyl-coenzyme A (coA) synthetase from Pseudomonas sp. has been used:
- as ligase in the synthesis of mevalonate derivatives of adenosine triphosphate (ATP)
- in in vitro fatty acylation assays
- in the synthesis of (14C)Vernoloyl-CoA (Va-CoA),(3) bisphosphonates derivatives of ATP(4) and (3H)Palmitate-CoA
Biochem/physiol Actions
Acyl coenzyme A synthetase proteins are involved in regulating and facilitating long-chain fatty acid transport in mammalian cells [1].
Acyl-coenzyme A (CoA) synthetase (ACS) enzyme catalyzes a two-step thioesterification reaction involving the conversion of free fatty acids (FAs) to CoA esters. The substrate for ACS varies from two carbon to 26 carbon FAs. It is involved in the activation of FAs for lipid metabolism and enables FA to participate in various cellular metabolic pathways.
Other Notes
1ユニットは、CoAの存在下で、pH 8.1、25°C、1分間に、1.0 μmolのAMPおよびオレオイルCoAをATPおよびオレイン酸から生成する酵素量です。
1 of 1
当該品目 | |||
|---|---|---|---|
| specific activity ≥2 units/mg protein | specific activity ≥3 units/mg protein | specific activity ≥100 units/mg solid | specific activity ≥3 units/mg solid |
| form powder | form lyophilized powder | form lyophilized powder | form lyophilized powder |
| shipped in dry ice | shipped in - | shipped in - | shipped in dry ice |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)