由来生物
mouse
リコンビナント
expressed in E. coli
結合体
unconjugated
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
79735, monoclonal
フォーム
lyophilized powder
分子量
antigen 38 kDa
交差性
human
以下との反応禁止
mouse
テクニック
western blot: 1-2 μg/mL
アイソタイプ
IgG2a
UniProtアクセッション番号
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... PLG(5340)
詳細
Angiostatin is an internal proteolytic fragment of plasminogen that has at least three kringle domains. This protein fragment functions as an endogenous angiogenesis inhibitor, and can also block endothelial cell proliferation,. Furthermore, angiostatin can specifically inhibit the growth of metastatic tumor.
Monoclonal Anti-Angiostatin recognizes human angiostatin. This antibody also recognizes plasminogen but shows no cross-reactivity with recombinant mouse angiostatin.
Monoclonal Anti-Angiostatin recognizes human angiostatin. This antibody also recognizes plasminogen but shows no cross-reactivity with recombinant mouse angiostatin.
免疫原
recombinant human angiostatin kringle 1-3 expressed in E. coli.
アプリケーション
Mouse monoclonal anti-angiostatin antibody can be used for western blot applications at 1-2 μg/mL.
物理的形状
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
13 - Non Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
最新バージョンのいずれかを選択してください：
José Ángel Nicolás-Ávila et al.
STAR protocols, 2(1), 100286-100286 (2021-01-26)
Cardiac exophers are membrane-bound extracellular vesicles released by cardiomyocytes with varied content and an average diameter of 3.5 μm. Here, we provide a detailed protocol to enable the identification and purification of cardiomyocyte-derived exophers by using fluorescence-activated cell sorting for downstream
Z Wu et al.
Biochemical and biophysical research communications, 236(3), 651-654 (1997-07-30)
Angiostatin, a 38 kDa internal fragment of plasminogen, is an antiangiogenic endothelial cell inhibitor. It regresses several primary and metastatic tumors in mice. To produce recombinant angiostatin for further structural and functional studies, the mouse angiostatin gene preceded by a
M S O'Reilly et al.
Cell, 79(2), 315-328 (1994-10-21)
The phenomenon of inhibition of tumor growth by tumor mass has been repeatedly studied, but without elucidation of a satisfactory mechanism. In our animal model, a primary tumor inhibits its remote metastases. After tumor removal, metastases neovascularize and grow. When
Y Cao et al.
The Journal of biological chemistry, 271(46), 29461-29467 (1996-11-15)
Recently we have identified angiostatin, an endogenous angiogenesis inhibitor of 38 kDa which specifically blocks the growth of endothelial cells (O'Reilly, M. S., Holmgren, L., Shing, Y., Chen, C. , Rosenthal, R. A., Moses, M., Lane, W. S., Cao, Y.
アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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