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Merck

352M-9

Sigma-Aldrich

Napsin A (MRQ-60) Mouse Monoclonal Antibody

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41
現在、価格および在庫状況を閲覧できません。

由来生物

mouse

品質水準

100
500

結合体

unconjugated

抗体製品の状態

culture supernatant

抗体製品タイプ

primary antibodies

クローン

MRQ-60, monoclonal

詳細

For In Vitro Diagnostic Use in Select Regions (See Chart)

フォーム

buffered aqueous solution

交差性

human

包装

vial of 0.1 mL concentrate (352M-94)
vial of 0.5 mL concentrate (352M-95)
bottle of 1.0 mL predilute (352M-97)
vial of 1.0 mL concentrate (352M-96)
bottle of 7.0 mL predilute (352M-98)

メーカー/製品名

Cell Marque®

テクニック

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

アイソタイプ

IgG1κ

コントロール

lung adenocarcinoma, renal cell carcinoma

輸送温度

wet ice

保管温度

2-8°C

視覚化

cytoplasmic

遺伝子情報

human ... NAPSA(9476)

詳細

Napsin is a pepsin-like aspartic proteinase in the A1 clan of the AA clade ofproteinases. Napsin A is involved in processing propeptide pulmonary surfactant protein B(proSP-B) in the lung. In normal, benign tissue, Napsin A has expressed in type II pneumocytesof the lung and proximal tubules of the kidney. Napsin A is a useful marker for lungadenocarcinoma.

品質


IVD

IVD

IVD

RUO

関連事項

Napsin A Positive Control Slides, Product No. 352S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

物理的形状

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

調製ノート

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

その他情報

For Technical Service please contact: 800-665-7284 or email: [email protected]

法的情報

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Frank Brasch et al.
The Journal of biological chemistry, 278(49), 49006-49014 (2003-09-18)
Surfactant protein B (SP-B) is a critical component of pulmonary surfactant, and a deficiency of active SP-B results in fatal respiratory failure. SP-B is synthesized by type-II pneumocytes as a 42-kDa propeptide (proSP-B), which is posttranslationally processed to an 8-kDa
Sanjay Mukhopadhyay et al.
The American journal of surgical pathology, 35(1), 15-25 (2010-12-18)
The availability of targeted therapies has created a need for precise subtyping of non-small cell lung carcinomas (NSCLCs). The aim of this study was to assess the utility of immunohistochemical markers in subtyping poorly differentiated NSCLC and to compare the
Annika Dejmek et al.
Diagnostic cytopathology, 35(8), 493-497 (2007-07-20)
The purpose of this study was to test napsin A as a diagnostic marker of metastatic lung adenocarcinoma in pleural effusions, and to compare its performance with TTF-1. Napsin A and TTF-1 reactivities were determined immunohistochemically on formalin-fixed paraffin embedded
Jaishree Jagirdar
Archives of pathology & laboratory medicine, 132(3), 384-396 (2008-03-06)
Immunohistochemistry is a very valuable and often used tool in the differential diagnosis of lung carcinomas whether primary or secondary to the lung. The most useful application is in distinguishing primary lung tumors from metastatic tumors to the lung from
Kentaro Inamura et al.
The American journal of surgical pathology, 29(5), 660-665 (2005-04-16)
Primary pulmonary adenocarcinomas with enteric differentiation (PAED) are mainly composed of tall-columnar cells that show similarity to intestinal epithelia and colorectal carcinomas. In this study, we analyzed the immunostaining profiles of 7 PAEDs in comparison with 14 metastatic colorectal carcinomas

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