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Merck

Y0000603

システム適合性用ロラタジン

European Pharmacopoeia (EP) Reference Standard

別名:

ロラタジン, 4-(8-クロロ-5,6-ジヒドロ-11H-ベンゾ[5,6]シクロヘプタ[1,2-b]ピリジン-11-イリデン-1-ピペリジンカルボン酸エチルエステル, ロラチジン

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About This Item

実験式(ヒル表記法):
C22H23N2O2Cl
CAS番号:
分子量:
382.88
MDL番号:
UNSPSCコード:
41116107
PubChem Substance ID:
NACRES:
NA.24

グレード

pharmaceutical primary standard

APIファミリー

loratadine

メーカー/製品名

EDQM

アプリケーション

pharmaceutical (small molecule)

フォーマット

neat

保管温度

2-8°C

SMILES記法

CCOC(=O)N1CC\C(CC1)=C2/c3ccc(Cl)cc3CCc4cccnc24

InChI

1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3

InChI Key

JCCNYMKQOSZNPW-UHFFFAOYSA-N

遺伝子情報

human ... HRH1(3269)

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詳細

この製品は薬局方標準品です。発行元の薬局方により製造・供給されています。MSDSを含む製品情報などの詳しい情報は、発行元の薬局方のウェブサイトよりご確認ください。

アプリケーション

Loratadine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生物化学的/生理学的作用

非鎮静性のヒスタミンH1-レセプタ-アンタゴニストです。

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

その他情報

Sales restrictions may apply.

関連製品

製品番号
詳細
価格

保管分類コード

11 - Combustible Solids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


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試験成績書(COA)

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文書ライブラリにアクセスする

R Wilkinson et al.
Brain injury, 13(12), 1025-1031 (2000-01-11)
The use of neuroleptics in the acute management of traumatic brain injury (TBI) is controversial and may be detrimental to recovery. The following case report describes a patient developing neuroleptic malignant syndrome (NMS) secondary to the use of haloperidol given
Nemanja Kolašinac et al.
International journal of pharmaceutics, 436(1-2), 161-170 (2012-07-10)
The present study investigates the possibility of using poloxamers as solubility and dissolution rate enhancing agents of the poorly water soluble drug substance desloratadine that can be used for the preparation of immediate release tablet formulation. Two commercially available poloxamer
H Ebrahimzadeh et al.
Analytica chimica acta, 767, 155-162 (2013-03-05)
In this work a molecularly imprinted polymer was developed as a selective sorbent for extraction of loratadine (as a model) in complex matrices followed by miniaturized homogeneous liquid-liquid extraction (MHLLE) for the first time. The molecularly imprinted polymer (MIP) which
J Kornhuber et al.
Neuropharmacology, 34(7), 713-721 (1995-07-01)
Amantadine (1-amino-adamantane) is clinically used for the management of Parkinson's disease and drug-induced extrapyramidal symptoms. It has previously been shown that amantadine is a low-affinity uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist with rapid blocking and unblocking channel kinetics (Ki-value at the
Mohamed El-Awady et al.
Journal of chromatography. A, 1309, 64-75 (2013-08-21)
The analysis of hydrophobic basic analytes by micellar electrokinetic chromatography (MEKC) is usually challenging because of the tendency of these analytes to be adsorbed onto the inner capillary wall in addition to the difficulty to separate these compounds as they

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