PHR2611

リファブチン

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: LM-427, アンサチピン(Farmitalia), アンサマイシン, ミコブチン(Farmitalia)
• 実験式（ヒル表記法）: C₄₆H₆₂N₄O₁₁
• CAS番号: 72559-06-9
• 分子量: 847.00
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to Ph. Eur. Y0000149; traceable to USP 1603800
• 詳細: Pharmaceutical Secondary Standard; Certified Reference Material
• APIファミリー: rifabutin
• 形状: solid
• CofA: current certificate can be downloaded
• 包装: pkg of 100 mg
• アプリケーション: pharmaceutical small molecule
• 保管温度: -10 to -25°C
• InChI: 1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1
• InChI Key: ATEBXHFBFRCZMA-VXTBVIBXSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

リファブチンは抗腫瘍性抗生物質です。分子シャペロンHSP-90を妨害してユビキチン化やタンパク質分解を促進するとともに、細菌のRNAポリメラーゼを不活化する作用があります。

アナリシスノート

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable