45661

ストリキニーネ

PESTANAL^®, analytical standard

• 別名: (−)-ストリキニーネ
• 実験式（ヒル表記法）: C₂₁H₂₂N₂O₂
• CAS番号: 57-24-9
• 分子量: 334.41
• Beilstein: 52979
• EC Number: 200-319-7
• MDL番号: MFCD00005941
• UNSPSCコード: 41116107
• PubChem Substance ID: 329756875

特性

• グレード: analytical standard
• 品質水準: 100
• 製品種目: PESTANAL^®
• シェルフライフ: limited shelf life, expiry date on the label
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 284-286 °C (lit.)
• アプリケーション: agriculture; cleaning products; cosmetics; environmental; food and beverages; forensics and toxicology; personal care; pharmaceutical (small molecule)
• フォーマット: neat
• SMILES記法: [H][C@@]12CC(=O)N3c4ccccc4[C@]56CC[N@H]7CC(=CCO1)[C@]([H])(C[C@@H]57)[C@]2([H])[C@]36[H]
• InChI: 1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1
• InChI Key: QMGVPVSNSZLJIA-FVWCLLPLSA-N

詳細

詳細

Strychnine is an alkaloid, available as a bioactive component in Semen Strychni, exhibiting analgesic, anti-inflammatory and anti-tumor effects. It is widely used in neurological research, treatment of genetic disorder nonketotic hyperglycinemia, treatment of stomach ailments, etc.

アプリケーション

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Strychnine may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to electrospray ionization mass spectrometry.

生物化学的／生理学的作用

けいれん薬です。グリシンレセプタ-のアンタゴニストですが、NMDAレセプタ-には結合しません。

法的情報

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06,GHS09
• シグナルワード: Danger
• 危険有害性情報: H300 + H310,H410
• 注意書き: P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310
• 危険有害性の分類: Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges