MABF155C

Anti-CD80 (mouse), APC, clone 16-10A1 Antibody

clone 16-10A1, from hamster(Armenian), Allophycocyanin conjugate

• 別名: T-lymphocyte activation antigen CD80, Activation B7-1 antigen (B7), CD80, CD80
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.43

特性

• 由来生物: hamster (Armenian)
• 品質水準: 100
• 結合体: Allophycocyanin conjugate
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: 16-10A1, monoclonal
• 化学種の反応性: mouse
• 包装: antibody small pack of 25 μg
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG
• UniProtアクセッション番号: Q00609
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Cd80(12519)

詳細

詳細

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

アプリケーション

This Anti-CD80 (mouse), APC, clone 16-10A1 Antibody is validated for use in Flow Cytometry for the detection of CD80.

品質

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.06 μg from a representative lot detected CD80 in one million C57Bl/6 splenocytes.

その他情報

Concentration: Please refer to lot specific datasheet.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable