MABF145C

Anti-TCR beta chain (mouse), FITC, clone H57-597 Antibody

clone H57-597, from hamster(Armenian), FITC conjugate

• 別名: Pre T-cell antigen receptor alpha, TCR beta chain
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

特性

• 由来生物: hamster (Armenian)
• 品質水準: 100
• 結合体: FITC conjugate
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: H57-597, monoclonal
• 化学種の反応性: mouse
• 包装: antibody small pack of 25 μg
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG
• UniProtアクセッション番号: P0C6B2
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Tcrb(21577)

詳細

詳細

The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g/d TCR.

免疫原

Immunogen information for this antibody is proprietary information.

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
免疫グロブリン及び免疫

This armenian hamster monoclonal Anti-TCR beta chain Antibody (mouse), FITC, clone H57-597, Cat. No. MABF1454 is validated for use in Flow Cytometry, for the detection of TCR beta chain.

品質

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 μg from a representative lot detected TCR beta chain in one million C57Bl/6 splenocytes.

物理的形状

Purified by size-exclusion chromatography

Purified Armenian Hamster monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

その他情報

Concentration: Please refer to lot specific datasheet.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable