MABC121

Anti-ALDH3A1, clone 10C7.1 Antibody

clone 10C7.1, from mouse

• 別名: Aldehyde dehydrogenase, dimeric NADP-preferring, ALDHIII, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: 10C7.1, monoclonal
• 化学種の反応性: human
• テクニック: immunohistochemistry: suitable; western blot: suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NP_000682
• UniProtアクセッション番号: P30838
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ALDH3A1(218)

詳細

詳細

Aldehyde dehydrogenase family 3 member A1 (ALDH3A1 or Aldh3A1) is a member of the aldehyde dehydrogenase (ALDH) superfamily. The ALDH family is a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. ALDHs are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. They are suggested to play a major role in the detoxification of alcohol-derived acetaldehyde. ALDH3A1 is shown to oxidize preferentially aromatic aldehyde substrates, and it may play a role in the oxidation of toxic aldehydes. ALDH3A1 is highly expressed in stomach, esophagus, lung, and cornea. It represents between 5 to 50% of the water soluble protein fraction in mammalian corneas and it is implied to protect the cornea from UV-induced oxidative stress.

免疫原

GST-tagged recombinant protein corresponding to the N-terminus of human ALDH3A1.

アプリケーション

Detect Aldehyde Dehydrogenase using this mouse monoclonal antibody, Anti-ALDH3A1, clone 10C7.1 Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ALDH3A1 in human stomach and lung tissues.

品質

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected ALDH3A1 in 10 µg of A549 cell lysate.

ターゲットの説明

~50 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.

物理的形状

Format: Purified

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable