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由来生物
mouse
抗体製品の状態
purified antibody
抗体製品タイプ
primary antibodies
クローン
1E1, monoclonal
化学種の反応性
mouse, human
テクニック
immunocytochemistry: suitable
western blot: suitable
入力
sample type neural stem cell(s)
sample type mesenchymal stem cell(s)
アイソタイプ
IgG1κ
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... ELK3(2004)
詳細
Serum response factor (SRF) is a nuclear transcription factor that binds to the serum response element (SRE), and is essential for embryonic development of the mesoderm, as well as for the maintenance of adult muscle cells and neurons. As this protein is involved in the downstream regulation of many immediate-early genes, it participates in a variety of cell functions, including cell cycle, apoptosis, cell growth, and cell differentiation. SRF is most commonly activated by serum, LPA, LPS, TPA, growth factors, including TNFalpha, as well as antioxidants and UV light.
特異性
A weak interaction with mouse has also been observed. Reactivity with other species has not been tested.
This monoclonal antibody recognizes SRF.
免疫原
Synthetic human SRF peptide, a.a. 406-508.
アプリケーション
Research Category
幹細胞研究
幹細胞研究
Research Sub Category
間葉幹細胞
神経幹細胞
間葉幹細胞
神経幹細胞
Detect SRF [Serum Response Factor] using this Anti-SRF [Serum Response Factor] Antibody, clone 1E1 validated for use in WB & IC.
Immunocytochemistry: Recommended working dilution is 1:500.
品質
(Based upon representative data from a previous lot).
Western Blotting: Recommended working dilution is 0.5 µg/mL.
Western Blotting: Recommended working dilution is 0.5 µg/mL.
ターゲットの説明
~52 kDa
物理的形状
Protein G Purified
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide.
保管および安定性
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MAB4369:
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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