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Merck

MAB4369

Sigma-Aldrich

Anti-SRF [Serum Response Factor] Antibody, clone 1E1

clone 1E1, from mouse

別名:

serum response factor (c-fos serum response element-binding transcription factor)

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About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41

由来生物

mouse

抗体製品の状態

purified antibody

抗体製品タイプ

primary antibodies

クローン

1E1, monoclonal

化学種の反応性

mouse, human

テクニック

immunocytochemistry: suitable
western blot: suitable

入力

sample type neural stem cell(s)
sample type mesenchymal stem cell(s)

アイソタイプ

IgG1κ

UniProtアクセッション番号

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... ELK3(2004)

詳細

Serum response factor (SRF) is a nuclear transcription factor that binds to the serum response element (SRE), and is essential for embryonic development of the mesoderm, as well as for the maintenance of adult muscle cells and neurons. As this protein is involved in the downstream regulation of many immediate-early genes, it participates in a variety of cell functions, including cell cycle, apoptosis, cell growth, and cell differentiation. SRF is most commonly activated by serum, LPA, LPS, TPA, growth factors, including TNFalpha, as well as antioxidants and UV light.

特異性

A weak interaction with mouse has also been observed. Reactivity with other species has not been tested.
This monoclonal antibody recognizes SRF.

免疫原

Synthetic human SRF peptide, a.a. 406-508.

アプリケーション

Research Category
幹細胞研究
Research Sub Category
間葉幹細胞

神経幹細胞
Detect SRF [Serum Response Factor] using this Anti-SRF [Serum Response Factor] Antibody, clone 1E1 validated for use in WB & IC.
Immunocytochemistry: Recommended working dilution is 1:500.

品質

(Based upon representative data from a previous lot).

Western Blotting: Recommended working dilution is 0.5 µg/mL.

ターゲットの説明

~52 kDa

物理的形状

Protein G Purified
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide.

保管および安定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

MAB4369:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Hui Liu et al.
Stem cells international, 2016, 2524092-2524092 (2016-01-23)
Resveratrol (trans-3,5,4'-trihydroxystilbene) (RSV) is a natural polyphenol with protective effects over cardiac tissues and can affect cell survival and differentiation in cardiac stem cells transplantation. However, whether this agent can affect cardiomyocytes (CMs) differentiation of induced pluripotent stem cells (iPSCs)
Norimichi Higurashi et al.
Molecular brain, 6, 19-19 (2013-05-04)
Dravet syndrome is a devastating infantile-onset epilepsy syndrome with cognitive deficits and autistic traits caused by genetic alterations in SCN1A gene encoding the α-subunit of the voltage-gated sodium channel Na(v)1.1. Disease modeling using patient-derived induced pluripotent stem cells (iPSCs) can

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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