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由来生物
mouse
品質水準
抗体製品の状態
ascites fluid
抗体製品タイプ
primary antibodies
クローン
mAB 1a, monoclonal
化学種の反応性
rabbit, mouse, human, rat
メーカー/製品名
Chemicon®
テクニック
flow cytometry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
アイソタイプ
IgG1
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
dry ice
ターゲットの翻訳後修飾
unmodified
特異性
Dihydropyridine calcium channel, a1 subunit as determined by Western blot (~210 kDa), immunoprecipitation and functional test. Membrane preparations are recommended. The mouse muscle cell line, BC3H1 functions as a good positive control cell line. Reactive with L-type calcium channel alpha1 subunit. Specific for small cell carcinoma and neuroblastoma by FACS analysis. No interaction with squamous cell carcinoma or with cardiac calcium chanel isoforms.
アプリケーション
Anti-Dihydropyridine-sensitive Calcium Channel α 1 Subunit Antibody, clone 1a is an antibody against Dihydropyridine-sensitive Calcium Channel α 1 Subunit for use in FC, IP & WB.
Western blot, immunoprecipitation and FACS.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
関連事項
Replaces: 06-422
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MAB427:
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Neuroscience, 141(1), 143-155 (2006-05-10)
Vertebrate photoreceptors consist of strictly delimited subcellular domains: the outer segment, ellipsoid, cell body and synaptic terminal, each hosting crucial cellular functions, including phototransduction, oxidative metabolism, gene expression and transmitter release. We used optical imaging to explore the spatiotemporal dynamics
Frontiers in cellular neuroscience, 13, 16-16 (2019-02-26)
Quantitative and qualitative evaluation of synapses is crucial to understand neural connectivity. This is particularly relevant now, in view of the recent advances in regenerative biology and medicine. There is an urgent need to evaluate synapses to access the extent
Visual neuroscience, 33, E009-E009 (2016-07-30)
Cacna1s encodes the α1S subunit (Cav1.1) of voltage-dependent calcium channels, and is required for normal skeletal and cardiac muscle function, where it couples with the ryanodine receptor to regulate muscle contraction. Recently CACNA1S was reported to be expressed on the
The Journal of cell biology, 136(1), 137-154 (1997-01-13)
Caveolae, flask-shaped invaginations of the plasma membrane, are particularly abundant in muscle cells. We have recently cloned a muscle-specific caveolin, termed caveolin-3, which is expressed in differentiated muscle cells. Specific antibodies to caveolin-3 were generated and used to characterize the
Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements.
Investigative Ophthalmology & Visual Science null
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