MAB10422

Anti-Plexin-A3 Antibody, clone 18A9.2

clone 18A9.2, from mouse

• 別名: plexin A3, PLEXIN-A3, plexin-A3, Sex chromosome X transmembrane protein of HGF receptor family 3, Semaphorin receptor SEX, plexin-4, Plexin-4
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: 18A9.2, monoclonal
• 交差性: rat, mouse, human
• テクニック: immunohistochemistry: suitable; western blot: suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NP_059984
• UniProtアクセッション番号: P51805
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... PLXNA3(55558)

詳細

詳細

Plexin-A3 is a cell surface receptor for semaphorin that controls signaling for neuronal axon regulation. Plexin-A3 is thought to play a role in Sema3F and Sema3A signaling, has been described as essential for dorsal turning of the corticospinal tract axons and may be an important contributor to development of hippocampal axonal projections. Plexin-A3 has been found expressed in newly-differentiated sympathetic neurons, but not their neural crest precursors, and together with Plexin-A4, functions cooperatively to regulate the migration of sympathetic neurons and then differentially to guide the sympathetic axons.

免疫原

GST-tagged recombinant protein corresponding to human Plexin-A3.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
神経変性疾患

Anti-Plexin-A3 Antibody, clone 18A9.2 is a Mouse Monoclonal Antibody for detection of Plexin-A3 also known as PLEXIN-A3, Semaphorin receptor SEX or Plexin-4 & has been validated in WB & IHC.

Western Blot Analysis: 1 µg/mL from a previous lot detected Plexin-A3 on 10 µg of HT-29 and NIH/3T3 cell lysates.

Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Plexin-A3 in colorectal carcinoma tissue.

品質

Evaluated by Western Blot in PC-12 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Plexin-A3 on 10 µg of PC-12 cell lysate.

ターゲットの説明

~220 kDa observed. The calculated molecular weight of this protein is 208 kDa; however, a higher band may be observed due to glycosolation.

物理的形状

Protein G

Format: Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
PC-12 cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable