FCMAB104A4

Anti-phospho H3 (Ser10) Antibody, clone 3H10 Alexa Fluor^™ 488

clone 3H10, from mouse, ALEXA FLUOR^™ 488

• 別名: H3 histone, family 3A, H3S10P, Histone H3 (phospho S10), H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B)
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: ALEXA FLUOR^™ 488
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 3H10, monoclonal
• 交差性: human
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NM_003493
• UniProtアクセッション番号: Q16695
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pSer10)
• 遺伝子情報: human ... HIST1H3F(8968)

詳細

詳細

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

特異性

Broad species cross-reactivity is expected.

Histone H3 phosphorylated at Ser10

免疫原

A proprietary immunogen based on a peptide sequence containing phospho-serine corresponding to residue 10 of human histone H3.

Epitope: Ser10

アプリケーション

Research Category
エピジェネティクス及び核内機能分子

アポトーシス及び癌

Research Sub Category
ヒストン

細胞周期、DNA複製及び修復

Anti-Phospho-Histone H3 (Ser10) Antibody, clone 3H10, Alexa Fluor^™ 488, is a Mouse Monoclonal Antibody for detection of Histone H3 phosphorylated at serine 10. This purified mAb, also known as H3S10p,
is labeled with Alexa Fluor 488 and validated for use in FC.

品質

Evaluated by Flow Cytometry with Jurkat cells.

ターゲットの説明

17 kDa observed

物理的形状

Protein G Purified

Purified mouse IgG1k conjugated to Alexa Fluor^™ 488 in PBS with 15mg/mL BSA and less than 0.09% sodium azide.

保管および安定性

Maintain refrigerated at 2-8oC in undiluted aliquots for up to 6 months from date of receipt. Protect from light.

アナリシスノート

Control
Jurkat Cells

法的情報

ALEXA FLUOR is a trademark of Life Technologies

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable