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由来生物
rabbit
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
精製方法
affinity chromatography
交差性
mouse, human, rat
交差性（ホモロジーによる予測）
chimpanzee (based on 100% sequence homology), bovine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology)
テクニック
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... SDC4(6385)
詳細
Syndecan-4 (Amphiglycan; Ryudocan core protein) is one of four members of the syndecan proteoglycan family. The syndecan proteins bind heparan sulfate and mediate the signaling of growth factors, such as fibroblast growth factor, that recognize and bind heparan chains. Unlike other members of this family, syndecan-4 is ubiquitously expressed, and is targeted to focal adhesions, possibly by a PKC-mediated pathway. Previous studies have reported an increase in focal adhesions in cells overexpressing syndecan-4. This protein also plays an important role in wound healing, by modulating the signaling of Rho-GTPases Rac1, RhoG, and RhoA.
特異性
This antibody recognizes the cytoplasmic domain of Syndecan-4
免疫原
Epitope: Cytoplasmic domain
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Syndecan-4.
アプリケーション
Research Category
細胞骨格
細胞骨格
Research Sub Category
細胞骨格シグナル伝達
細胞骨格シグナル伝達
Immunohistochemistry Analysis: A 1:100-1,000 dilution from a representative lot detected Syndecan-4 in human lung carcinoma and in distal tubules of normal human kidney tissue.
This Anti-Syndecan-4 Antibody is validated for use in Western Blotting, IHC(P) for the detection of Syndecan-4.
品質
Evaluated by Western Blot in HEP2 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Syndecan-4 in 10 µg of HEP2 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Syndecan-4 in 10 µg of HEP2 cell lysate.
ターゲットの説明
~80/32 kDa observed
物理的形状
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
保管および安定性
Stable for 1 year at 2-8°C from date of receipt.
アナリシスノート
Control
HEP2 cell lysate
HEP2 cell lysate
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
ABT157:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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