ABN483

Anti-RTP801 Antibody

from rabbit, purified by affinity chromatography

• 別名: DNA damage-inducible transcript 4 protein, HIF-1 responsive protein RTP801, Protein regulated in development and DNA damage response 1, REDD-1, RTP801
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 交差性: mouse, human
• テクニック: immunohistochemistry: suitable; western blot: suitable
• UniProtアクセッション番号: Q9NX09
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... DDIT4(54541)

詳細

詳細

HIF-1 responsive protein RTP801, also known as DNA damage-inducible transcript 4 protein, is a member of the DDIT4 family regulating cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. RTP801 is widely expressed with lowest levels in brain, skeletal muscle, and intestine.

免疫原

KLH-conjugated linear peptide corresponding to human RTP801.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
ニューロン発生

Detect HIF-1 responsive protein RTP801 using this rabbit polyclonal antibody, Anti-RTP801 Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected RTP801 in mouse kidney tissue.

品質

Evaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected RTP801 in 15 µg of human kidney tissue lysate.

ターゲットの説明

~25 kDa observed. Uncharacterized bands may appear in some lysates.

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Human kidney tissue lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable