詳細
The synaptophysin-like protein 1, also known as pantophysin, is a homolog of the neuroendocrine-specific protein synaptophysin, with the highest level of homology across its four transmembrane domains. Unlike synaptophysin however, SYPL1 is ubiquitously expressed and found in small cytoplasmic transport vesicles regardless of their content. SYPL1 is thought to play a multifunctional role in vesicle biogenesis and transport and is a component of adipocyte transport vesicles, and thus may be involved in adipocyte secretion. SYPL1 also interacts with vesicle-associated membrane protein 2 (VAMP-2) in adipocytes and associates with GLUT4-containing vesicles.
免疫原
KLH-conjugated linear peptide corresponding to human SYPL1.
アプリケーション
Research Category
ニューロサイエンス
Research Sub Category
ニューロン発生
Anti-SYPL1 Antibody is a highly specific rabbit polyclonal antibody, that targets Synaptophysin-like protein 1 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected SYPL1 in human cerebellum, colon, and thalamus tissues.
品質
Evaluated by Western Blotting/Peptide Inhibition Assay in human brain tissue lysate.
Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected SYPL1 in 15 µg of human brain tissue lysate.
ターゲットの説明
~28 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~26 kDa and ~29 kDa
物理的形状
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
保管および安定性
Stable for 1 year at 2-8°C from date of receipt.
アナリシスノート
Control
Human brain tissue lysate
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.