ABF206

Anti-TRIM5 alpha Antibody

from rabbit, purified by affinity chromatography

• 別名: Tripartite motif-containing protein 5, RING finger protein 88
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 交差性: human
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProtアクセッション番号: Q9C035
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... TRIM5(85363)

詳細

詳細

Tripartite motif-containing protein 5 (TRIM5), also known as RING finger protein 88 (RNF88), is a member of the TRIM/RBCC family defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. TRIM5 isoform alpha is a retrovirus restriction factor, which mediates species-specific, early block to retrovirus infection.

特異性

This antibody recognizes the intermediate domain of TRIM5 alpha.

免疫原

KLH-conjugated linear peptide corresponding to the intermediate domain of human TRIM5 alpha.

アプリケーション

Detect Tripartite motif-containing protein 5 using this rabbit polyclonal antibody, Anti-TRIM5 alpha Antibody validated for use in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected TRIM5 alpha in human stomach tissue.

Immunofluorescence Analysis: 10 µg/mL from a representative lot detected TRIM5 alpha in human stomach cells.

品質

Evaluated by Western Blotting in human stomach, thymus, and uterus tissue lysates.

Western Blotting Analysis: 2 µg/mL of this antibody detected TRIM5 alpha in 15 µg of human stomach, thymus, and uterus tissue lysates.

ターゲットの説明

~55 kDa observed. Uniprot describes 6 isoforms ranging between ~30 kDa and ~56 kDa Uncharacterized bands may appear in some lysates.

アナリシスノート

Control
Human stomach, thymus, and uterus tissue lysates

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable