ABE374

Anti-DAZ Antibody

from rabbit, purified by affinity chromatography

• 別名: Deleted in azoospermia protein 1
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 交差性: mouse, rat, human, pig, horse
• 交差性（ホモロジーによる予測）: equine, porcine, chimpanzee, bovine, rhesus macaque
• テクニック: immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBIアクセッション番号: NP_004072.3
• UniProtアクセッション番号: Q9NQZ3
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... DAZ1(1617)

詳細

詳細

DAZ is an RNA-binding protein that belongs to the DAZ family of proteins required for normal growth, development, and fertility. The DAZ family of proteins have one or more RNA recognition motif (RRM) domains and multiple DAZ repeats. Mammalian DAZ is widely expressed in adults with high levels of expression in testis. Frequent deletion of the DAZ genes suggests that DAZ plays an important role in spermatogenesis. It was even proposed that DAZ family proteins are involved in mRNA metabolism during spermatogenesis.

特異性

This antibody recognizes the N-terminus of DAZ. This antibody demonstrates cross-reactivity with DAZ2, DAZ3, DAZ4, and DAZL each of which contains repeats of the DAZ gene.

免疫原

KLH-conjugated linear peptide corresponding to the N-terminus of human DAZ.

アプリケーション

Anti-DAZ Antibody is a Rabbit Polyclonal Antibody for detection of DAZ also known as Deleted in azoospermia protein 1 & has been validated in WB, IHC(P).

Immunohistochemistry Analysis: A 1:400 dilution from a representative lot detected DAZ in human testis tissue.

品質

Evaluated by Western Blot in human testis tissue lysate.

Western Blot Analysis: 1 µg/mL dilution of this antibody detected DAZ in 10 µg of human testis tissue lysate.

ターゲットの説明

~83 kDa calculated. Additional bands due to polymorphic expression of DAZ as well as cross-reactivity with DAZ2, DAZ3, DAZ4, and DAZL with calculated molecular weights of ~33 kDa, 37 kDa, 75 kDa, and 100 kDa may be observed in some cell lysates (Poongothai, J., et al. (2009). Singapore Med J. 50(4):336-347; Kim, B., et al. (2009). Hum Reprod. 24(6):1507-1515). This antibody detects DAZ proteins at ~36 kDa, ~80 kDa, and ~105 kDa

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable